ABSTRACTThe incidence of isoniazid (INH) resistant Mycobacterium tuberculosis is increasing globally.This study aimed to identify the molecular mechanisms behind the development of INH resistance in M.tuberculosis strains collected from the same patients during the standard course of treatment.Three M.tuberculosis strains were collected from a pati
Background: Association between obesity and dysregulation of autonomic functions has long been established and is believed to be the cause of increased risk of cardiovascular morbidity and mortality.Furthermore, early detection of impaired autonomic functions and hence timely intervention can prevent many of the obesity related cardiovascular compl
Abstract Background Massive text mining of the biological literature holds great promise of relating disparate information and discovering new knowledge.However, disambiguation of gene symbols is a major bottleneck.Results We developed a simple thesaurus-based disambiguation algorithm that can operate with very little training data.The thesaurus co
Abstract Morchella species are well known world-round as popular and prized edible fungi due to their unique culinary Handheld Sweeper flavor.Recently, several species have been successfully cultivated in China.However, their reproductive modes are still unknown, and their basic biology needs to be elucidated.Here, we use the morel genome informati